Sandimmun Neoral and Cyclosporine for FSGS Patients

FSGS, focal segmental glomerulosclerosis, is one condition in which less than 50% of glomeruli, kidney filters, are scarred. To manage FSGS, sandimmun neoral and cyclosporine both are used commonly.

Firstly, make clear the causes of FSGS kidney disease

There are many factors that can cause FSGS such as poisoning damage, humoral immune disorders and hemodynamics changes. All of these factors can lead to damage to capillary walls, so large molecular immunoglobulin accumulates and combine with C1q and c3. Finally, podocyte degenerates and separates from basement membrane.

How does sandimmun neoral and cyclosporine work for FSGS

Both of these two medications can help protect transplanted liver, kidney and heart by fighting against rejection reaction. Additionally, these medications can help treat immune diseases, because they can inhibit immune system and immune reactions.

Most often, after about six months, FSGS patients’ proteinuria can be reduced obviously and their illness condition can be alleviated. However, if reducing the dosage or stopping the medication, FSGS relapses easily. What’s worse, sandimmun neoral and cyclosporine are easy to cause some side effects including renal toxicity, liver toxicity, high blood pressure, nausea, vomiting, difficult breathing, infections, and so on. Thereby, to treat FSGS kidney disease completely, a systemic treatment is needed.

Alternative treatments for FSGS kidney disease

Since FSGS is related with immune disorder, Immunotherapy is one good choice for these patients. On one hand, immune diagnosis can guide doctors to develop a correct treatment plan, and immune blockage, tolerance and clearance can cleanse the internal environment thoroughly. On the other hand, immune protection and adjustment can help regulate immune system and repair damaged kidney cells. Therefore, FSGS can be treated from the root cause. What’s better, this therapy is natural and usually doesn’t produce any severe side effect.

Now, we have known different treatment options for FSGS. No matter which one you want to take, make sure you have consulted your doctor or doctor online in detail.

Tag: FSGS FSGS Treatment

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