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What Are the Causes of Renal Parenchyma Disease

2014-04-19 02:26

What Are the Causes of Renal Parenchyma DiseaseRenal Parenchymal Disease is not a single disease, and it can be caused by a variety of reasons. If not treated well, it will develop into kidney failure eventually. Thereby, it necessary to learn about the causes.

Each kidney is consisted of millions of nephrons in the renal parenchymal area. And the glomeruli within the nephrons can help excreted wastes, metabolic products, extra fluid, etc out of the body. Once renal parenchymal disease occurs, kidneys will fail to do its job properly.

Kidney stones

When kidney stones move in the ureter, the risk of presenting chronic urinary tract infection will be increased. Under certain circumstances, the renal parenchymal may become scarred.


According to the statistics, long-term uncontrolled high blood sugar level will put extra strain on the filtering units(glomeruli) and eventually lead to renal parenchymal disease.

High blood pressure

High blood pressure can cause damage to the blood vessels. Over time, the arteries around the kidneys may become narrow or even harden. In this case, less blood, oxygen and nutritions will be transported to the renal parenchymal.

Lupus erythematosus

It is estimated that about 50% lupus erythematosus patients will experience lupus nephritis. In lupus, the abnormal antibodies will mistakenly attack the healthy cells, including those within the nephrons. When renal parenchymal damage occurs, the kidneys’ filtering function will be damaged. Additionally, there can also be inflammatory reactions, which will put extra burden to the glomeruli.

Except for the above conditions, chronic pyelonephritis, polycystic kidney disease, obstructions, autoimmune disorders, hydronephrosis, interstitial nephritis, reflux kidney disease and so on are also related to renal parenchyma disease.

After the above analysis, we believe you have learned about the causes of renal parenchymal disease, if there is anything unclear, you can email us or consult with our online doctor!

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