Nephrotic Syndrome Treatment

According to the sensitivity to steroids, Nephrotic Syndrome is classified into three types, namely steroid-sensitive NS, steroid-dependent NS, and steroid-resistant NS. In this article, let’s talk about treatment for steroid-dependent NS.

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Steroid-Dependent Nephrotic Syndrome: How to Treat It

2018-09-14 08:32

Steroid-Dependent Nephrotic Syndrome: How to Treat ItAccording to the sensitivity to steroids, Nephrotic Syndrome is classified into three types, namely steroid-sensitive NS, steroid-dependent NS, and steroid-resistant NS. In this article, let’s talk about treatment for steroid-dependent NS.

The routine treatment for nephrotic syndrome is steroid and immunosuppressive agents. These medicines only can cause temporary relief, but can not control the disease effectively, especially for those with steroid-dependent nephrotic syndrome (SDNS). Once the steroid dose is reduced or stopped, the disease will relapse.

Why does nephrotic syndrome relapse frequently?

Nephrotic syndrome is an immune-mediated kidney disorder, in which the immune system fails to function improperly. Immune system is a defensive system of the body and can protect the body against outside harmful substances. However, in nephritic syndrome, the immune system fails to protect the body. When outside harmful substances like infection, colds and so on attack the body as antigens, the immune system will produce antibodies to fight against the antigens. In right condition, after the antibodies defeat the antigens, they will form immune complexes. These immune complexes will be filtered out of body in right condition.

However, in nephritic syndrome, these immune complexes will flow into kidneys and deposit in glomeruli. These immune complexes firstly will cause inflammation in kidneys and affect the glomeruli. Glomerular filtration membrane has barrier function and can stop glomeruli from passing through glomeruli. However, once the glomeruli become impaired, the permeability of glomerular filtration membrane will increase. As a result, a lot of protein will leak into urine.

Steroids and immunosuppressants can suppress the inflammation in kidneys and reduce the permeability of glomerular filtration membrane. Thereby, the patients can have a remission after a period of treatment. However, the immune disorder can not be corrected and those immune complexes from both blood and kidneys can not be eliminated. Whenever there is a triggering factor like cold, the inflammation in kidneys will recur. Hence, protein will leak into urine. Definitely, frequent relapses of nephrotic syndrome will certainly cause progressive renal function deterioration. What's worse, long-term use of steroids and immunosuppressive drugs can cause a lot of serious adverse effects, especially for children like growth retardation, endocrine disorders, osteoporosis etc.

Treatment for Steroid-Dependent Nephrotic Syndrome

In Beijing Tongshantang Hospital of Traditional Chinese Medicine, Toxin-Removing Treatment is often used. It is composed of a variety of therapies, not only oral Chinese medicine, but also external Chinese therapies. Those therapies can work together to dissolve immune complexes and eliminate them from the kidneys and blood. They can also restore the balance of anti-inflammatory cytokines and pro-inflammatory cytokines to reduce renal inflammation and control the disease from getting worse. Moreover, they can improve blood circulation and increase blood flow into kidneys and provide the damaged kidneys with enough essential elements to speed up kidney recovery. After about one week’s treatment, swelling will fade away. After about half month’s treatment, proteinuria will be reduced. After about one month’s treatment, Nephrotic Syndrome will be under control, and renal condition will get improved. With the continuous improvement of illness condition, you can reduce the dependence on steroids.

Now you know the treatment for steroid-dependent Nephrotic Syndrome. For more information on our hospital and our treatment, please leave a message below or contact online doctor.

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