Lupus Nephritis Diagnosis

When it comes to renal biopsy, many patients have various concerns, after all, it is invasive. Then is renal biopsy a must for Lupus Nephritis patients?

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Is Renal Biopsy A Must for Lupus Nephritis Patients

2018-08-09 09:17

Is Renal Biopsy A Must for Lupus Nephritis PatientsWhen it comes to renal biopsy, many patients have various concerns, after all, it is invasive. Then is renal biopsy a must for Lupus Nephritis patients?

1. Lupus nephritis patients can have a clear diagnosis of disease by renal biopsy.

Although the diagnosis of systemic lupus erythematosus depends on clinical manifestations and laboratory test results, whether patients with lupus have lupus nephritis or not needs to be confirmed by renal biopsy. In most cases, it is indeed Lupus Nephritis, but in some cases, it may be other glomerulonephritis that causes kidney damage to Lupus patients. Renal biopsy can give you an accurate judge.

2. The treatment of lupus nephritis is determined by renal biopsy.

By pathological examination of the kidney, lupus nephritis can be divided into six types according to different pathological manifestations.

Class I: Minimal mesangial lupus nephritis

Class II: Mesangial proliferative lupus nephritis

Class III: Focal lupus nephritis (active and chronic, proliferative and sclerosing)

Class IV: Diffuse lupus nephritis (active and chronic, proliferative and sclerosing, segmental and global)

Class V: Membranous lupus nephritis

Class VI: Advanced sclerosis lupus nephritis

Different pathological types may have similar clinical manifestations, and it is difficult to distinguish them through clinical data. And different types of lupus nephritis may require different treatment options.

3. Renal biopsy may assist in the discovery of many lesions that are difficult to determine by purely medical history and laboratory examination.

Renal biopsy may assist in the discovery of many lesions that are difficult to determine by purely medical history and laboratory examination. These lesions may often play an important role in the choice of treatment and the prognosis of the disease. For example, large dose of glucocorticoid pulse therapy is needed when there are a lot of crescent formation and fibrinoid necrosis. If thrombotic microvasculopathy appear, it may be necessary to carry out plasma exchange therapy.

4. Repeated kidney biopsy at the appropriate time is of great importance for timely and accurate judgment of the changes in the condition and therapeutic effect, as well as for guiding the adjustment of treatment regimen.

An important characteristic of lupus nephritis is that it can undergo pathological type transformation with the development of the disease and the effect of treatment. When the type changes, the treatment plan should be adjusted timely to control the disease well.

Is renal biopsy a must for Lupus Nephritis patients? From the above, we can see that it is. If you do not like invasive method, welcome to Beijing Tongshantang Hospital of Traditional Chinese Medicine. We have advanced diagnosis methods and treatment to help you get well soon. For more information on Lupus Nephritis, please leave a message below or contact online doctor.

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