Five Organs May Be Affected By Kidney Failure

2018-11-27 03:27

At present, no matter nephrologists or kidney patients, they are more concerned about which foods, drugs and behaviors can damage the kidney, and which diseases can damage the kidney, as well as proteinuria, serum creatinine and other indicators. They seldom concern after kidney damage, which organs will be affected. After all, the kidney is not an isolated organ. In other words, a person with kidney disease whose creatinine levels rise rapidly is more likely to have heart, liver, brain, lung, gastrointestinal tract and other problems. Which organs will be affected by kidney failure?

1. Lung

Acute lung injury is a common complication of kidney disease.

In patients with end-stage renal disease (ESRD), the accumulation of toxins in the body may have adverse effects on pulmonary ventilation. Fluid overload can cause alveolar edema and metabolic acidosis, leading to hyperventilation in kidney patients.

In clinical practice, respiratory complications caused by acute kidney injury, include pulmonary edema and respiratory failure, which often require mechanical ventilation, and mechanical ventilation time is longer, and the possibility of withdrawal is less.

2. Heart

The heart and kidney are connected, so damage to one organ can lead to dysfunction of another organ, which is clinically known as cardiorenal syndrome (CRS).

For example, fluid overload caused by kidney disease can impair myocardial function and induce maladaptive remodeling. The involvement of uremic toxin can cause cardiovascular toxicity and increase the risk of myocardial ischemia.

3. Brain

High levels of toxins in people with kidney failure can cause brain damage, which is manifested as erratic behavior, inattention, hyperreflexia, changes in consciousness, seizures, and even death.

The lower the kidney function, the higher the creatinine, and the more severe the brain damage.

4. Liver

We have known the relation of liver and kidney clearly. However, doctors are generally concerned about renal dysfunction caused by liver disease - hepatorenal syndrome, but rarely care about the impact of acute kidney injury on the liver.

In recent years, studies have shown that acute kidney injury can promote the oxidation, inflammation and apoptosis of liver cells and increase the permeability of hepatic blood vessels. In addition, acute kidney injury can have an impact on drug metabolism in the liver, and patients taking drugs for liver disease need to be vigilant.

5. Gastrointestinal tract

Gastrointestinal tract is also an organ easily involved by kidney disease, but it is easy to be ignored by people. In recent years, more and more attention has been paid to it.

Both patients and laboratories have shown that intestinal microbes and kidney diseases can interact. However, most of them are studying how intestinal microorganisms damage the kidney, and few are studying how the gastrointestinal tract is affected after kidney damage.

Summary

When kidneys are damaged, it is likely for almost all organs to be affected. Therefore, you should pay attention to your transaminase, ECG, carbon dioxide, etc. Once you find any abnormalities, please go for medical treatment timely.

The above material is intended for informational purposes only. For specific treatment recommendations, please consult a physician.

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