Iga Nephropathy Treatment

Is fish oil recommended for IgA Nephropathy? Maybe the authoritative data is most persuasive. For the effectiveness of fish oil, four researches have been taken. The first two researches were taken in Australia and Sweden, respectively invo

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Is Fish Oil Recommended For IgA Nephropathy

2014-04-13 00:50

Is Fish Oil Recommended For IgA NephropathyIs fish oil recommended for IgA Nephropathy? Maybe the authoritative data is most persuasive.

For the effectiveness of fish oil, four researches have been taken. The first two researches were taken in Australia and Sweden, respectively involved in 37 and 32 patients within two years and half a year. The other group researches were in America and Japan with 106 and 20 patients, having observed for two years and one year. Among the four researches, America and Japan proved that fish oil is good for the treatment of IgA Nephropathy. You may still doubt about that conclusion because the latter researches have involved more patients and took longer times. However we can at least draw an conclusion that: There are 75% possibility of fish oil’s protection (even a slight one) for kidney.

Now you may want to know the reasons. The following article may help you get the answers. Fish oil contains large amounts of omega-3 polyunsaturated fatty acids (n-3 PUFA). Its benefits have been reported in recent epidemiologic studies and randomized clinical trials in a variety of cardiovascular and autoimmune diseases. As we all know, IgA Nephropathy occurs due to the deposition of immune complex, so it is also an autoimmune disease. That is why fish oil is used to treat IgA Nephropathy.

The mechanism of its protection for kidneys is divided into four aspects:

1. Anti-inflammation

The n-3 PUFA can affect arachidonic acid metabolism, reducing inflammatory mediators through epoxidase and lipoxidase.

2. Prevent glomerular mesangial cell proliferation

3. Improve microcirculation

Fish oil can affect the prostaglandin synthesis by interfering epoxidase. That will increase diastolic prostaglandin which is helpful for dilating blood vessels. As a result, renal interstitium pressure can be lowered. Therefore, the microcirculation of glomerulus capillary will be improved, thus more blood and oxygen can be supplied.

Now that it is good for IgA Nephropathy patients, how much should they take for one day? Experts say that treatment for 2 years with a daily dose of 1.8 g of EPA and 1.2 g of DHA is OK. You can buy it in your local pharmacy.

If you want to learn more about IgA Nephropathy diet or treatment, you can email to kidney-symptoms@hotmail.com or leave a message below. We are glad to help.

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