Loss Of Appetite And High Creatinine
Many patients with high creatinine can find they have loss of appetite, and it is necessary for them to have a better understanding about this aspect.
What can we know from high creatinine?
High creatinine often means patients already have severe kidney damage.
Kidney has the function of excreting out the wastes and toxins in blood. While creatinine is a toxin to our body, and almost all creatinine will be excreted out in the same day. So high creatinine means patients has kidney damage.
In fact, kidney has strong compensation, and patients will not have any problem if more than half kidney function is normal. It is also to say, if patients have high creatinine level, it may mean they already have severe kidney damage.
Why do patients with high creatinine have loss of appetite?
A major reason of patient’s loss of appetite is the accumulation of leptin. As we know, patients with high creatinine can have many disorders in their body, like inflammation, high level of cholesterol in blood, etc. While these factors can stimulate patients’ hormone excretion and cause patients to excrete more leptin. Leptin can inhibit the excretion of neuropeptide Y excreted by hypothalamus, while this can affect patients’ appetite, and cause patients to have inappetence.
Another reason of loss of appetite is the accumulation of urea nitrogen and other wastes. As we know, high creatinine means patients already have severe kidney damage, and then many substances will accumulate in patients’ blood. While many toxins can stimulate patients gastrointestinal system, which can cause patients to have loss of appetite. Besides, the bacteria in intestines can compound urea nitrogen and produce ammonia. While ammonia has strong irritation to gastrointestinal system, and patients often have loss of appetite in this condition.
In addition, if patients with high creatinine level have nerve problem, they can also have loss of appetite.
While every patient need to accept treatment and care based on their own condition, and it is important for patients to make changes under their doctor’s guidance. Besides, if you have question, you can also consult our online experts, and we are glad to help you.
