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End Stage Renal Disease and Hypoglycemia

2014-05-27 03:38

End Stage Renal Disease and HypoglycemiaAbout the relationship of End Stage Renal Disease (ESRD) and Hypoglycemia, a survey has been made, from which we know some potential causes of hypoglycemia.

Of a total of 1545 admissions of end stage renal failure patients, fifty-six (3.6%) were admitted during a ten-year period with hypoglycemia. Thirty-eight of them were diabetic while the others were non-diabetic patients. Drug-induced hypoglycemia is the most common situation, being found in 26 (46%) patients. In 22 (39%) cases, sepsis was the contributing cause of hypoglycemia. Severe malnutrition caused 7% of hypoglycemic episodes. Of the patients, 18 (32%) with ESRD eventually died, and none of them were from the drug-induced group. However, mortality rate in the sepsis-induced hypoglycemia group was 66% and the malnutrition group was 17%. Thus, hypoglycemia is frequent in ESRD patients, and may be fatal if associated with drugs, sepsis or malnutrition.


1. Drugs: Medications that can cause drug-induced hypoglycemia include bactrim (an antibiotic), beta-blockers, haloperidol, insulin, MAO inhibitors, metformin when used with sulfonylureas, pentamidine, quinine, sulfonylureas

2. Sepsis: The mechanism for hypoglycemia with sepsis is not well defined. Depleted glycogen stores, impaired gluconeogenesis and increased peripheral glucose utilization may all be contributing factors.

3. Malnutrition: It is a common cause of hypoglycemia either in healthy persons or end stage renal disease patients.


Most people feel symptoms of hypoglycemia when their blood sugar is 70 mg/dL or lower, including:

1. Early symptoms of hypoglycemia may include confusion, dizziness, feeling shaky, hunger, headaches, irritability, pounding heart, racing pulse, pale skin, sweating, trembling, weakness, anxiety

2. Without treatment, more severe hypoglycemia symptoms may develop, including headache, poor concentration, numbness in mouth and tongue, sleep problems, coma.

For end stage renal disease patients, a regular test of blood sugar level and a healthy diet are helpful treatments. For detailed treatments, you can consult our experts online or leave a message below.

As for you own illness conditions, you can get some guidance related to diet, exercise, medicines or some natural remedies. The online consultation service is free. Please remember to leave your email address, or phone number so that we can contact you and help you!
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