In Stage 4 CKD (chronic kidney disease), a series of symptoms will occur, such as edema, anemia, vomiting, itching, high blood pressure, proteinuria and so on. At the same time, high BUN (blood urea nitrogen ) and high creatinine level may be induced. Then, what is BUN and creatinine level in Stage 4 CKD?
Stage 4 of chronic kidney disease has a severely diminished GFR (glomerular filtration rate) which is about 15~29ml/min. Kidneys fail to function properly and impaired kidneys cannot remove waste products and toxins from the body.
BUN (blood urea nitrogen) is the end-product of protein metabolism. Usually, it has been taken as one of the indicators to reflect kidney function. The normal range of BUN level is 3.2~7.1mmoL/L in adults and 1.8~6.5mmoL /L in children. Once the blood test shows an index beyond this range, it means high BUN level.
Creatinine is a breakdown product of creatine phosphate in muscle. Its normal range is 0.6~1.2mg/dL for male and 0.5~1.1mg/dL for female. If the blood test shows an index beyond this range, it means high creatinine level.
Now, you know clearly the BUN and creatinine level in all stages of Chronic Kidney Disease from the following chart.
|CKD Stages||GFR||BUN level||Creatinine level|
|CKD Stage 1||≥90ml/min||normal||normal|
|CKD Stage 2||89~60ml/min||7.14~8.39mmoL/L||1.3~2.0mg/dl|
|CKD Stage 3||59~30ml/min||7.14~8.39mmoL/L||2.0~5.0mg/dl|
|CKD Stage 4||29~15ml/min||8.39~21.42mmoL/L||5.0~8.0mg/dl|
|CKD Stage 5||≤14ml/min||＞21.42mmoL/L||≥8.0mg/dl|
In Stage 4 CKD, high BUN level and high creatinine level actually can cause further damage on kidneys. Therefore, a timely and active treatment is important to control symptoms and prevent worsening illness condition. If you have still anything unclear about elevated BUN and creatinine level, please inform us by emailing to firstname.lastname@example.org or leave a message below directly.