Both swelling and proteinuria are the symptoms of Chronic Kidney Disease (CKD). Actually, there is a link between swelling and proteinuria. Swollen ankles can be a result of proteinuria. How does that happen? Follow me, and you will know the answer.
► Proteinuria has reduced the blood volume in the body
Proteinuria means a large amount of protein (>3.5g per day) leakage out of the body. Then, hypoproteinemia occurs, making fluid in the plasma move out. Therefore, the effective blood volume reduces a lot.
The brains thus receive the signals of reduced blood volume, and start the RAS (Renin-Angiotensin-Aldosterone) system, increasing the reabsorption of sodium ions. Meanwhile, the signal also decrease the elimination of sodium by kidneys.
As a result of above reasons, high level of sodium and water build up in the body, leading to swelling. Your face, hands, legs, feet, and ankles can become swollen.
► Proteinuria results in hypoproteinemia, leading to a decreased plasma colloid osmotic pressure
Large amounts of protein is discharged by the damaged kidneys, thus resulting in negative nitrogen balance. Then, the plasma colloid osmotic pressure drops, which will make the fluid in the blood vessels move into the spaces of tissues. That’s why swelling occurs.
Am I clear now? Next, I would like to share with you some suggestions to relieve swollen ankles.
► Treatments for proteinuria include:
1. Angiotensin-converting enzyme inhibitor (ACE) or angiotensin receptor blocker (ARB) medications to lower blood pressure and protect kidney function
2. Dietitian consultation and a healthy meal plan
3. Diuretics: Dandelion, nettle, poria cocos, rhizome of lalang, and grifola are Chinese herbs and can be used as natural diuretics.
4. Insulin or other medications to help control blood sugar levels in people with diabetes
5. Low-protein diet
7. Low-sodium diet
8. Treatment of any underlying chronic conditions
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