Blood purification is one great breakthrough in kidney replacement therapy. Compared with dialysis, blood purification uses various methods that can remove not only small molecular waste substances, just as dialysis does, but also moderate and large molecular waste substances. Therefore, this therapy can protect remaining kidney function better and keep the internal environment stable.As introduced by doctors in our hospital, several methods are often used in blood purification, and they include:
Hemodialysis is the most commonly used method to replace damaged kidneys’ work, but it can only do a part of kidneys’ work. These include removing small molecular waste products and toxins, easing swelling, regulating blood pressure and keeping electrolyte balance. However, hemodialysis is unable to work as effectively as healthy kidneys, so the longer patients on dialysis, the more side effects and complications they may have.
Compared with hemodialysis, hemofiltration can also filter out moderate molecular waste products and toxins besides small molecular ones. Therefore, it can help protect remaining kidney function and maintain stable hemodynamics better.
In addition to kidney disease, drug poisoning, too high blood fat, high PTH, etc, can also be managed by hemoperfusion. This is because this blood purification method focuses on eliminating toxic substances from the body. If kidney patients are suffering from serious skin itching, hemoperfusion can help a lot.
Immune adsorption has an obvious superiority on treating autoimmune disease like Lupus Nephritis, because it is able to remove most of abnormal immune complexes out of the body. Therefore, this methods suit for patients whose kidney disease is caused by deposits of immune complexes.
Plasma exchange is one method that exchanges polluted blood plasma with healthy plasma. Then, the harmful substances in the blood can be removed out.
If patients have IgA Nephropathy, anti-glomerular basement membrane (GBM) disease, Lupus, vascular disease and FSGS, they can get a great improvement from plasma exchange.
CRRT refers to continuous renal replacement therapy that can remove small, moderate and large molecular waste products and toxins from the body. This treatment can help deal with some emergent diseases. This is very effective on protecting remaining kidney function and preventing relative complications.
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