What Is The Effective Treatment for Refractory Hematuria In IgA Nephropathy

Questions: 1. What are stages and symptoms of IgA Nephropathy?

2. Why IgA Nephropathy is difficult to be treated?

3. Are Chinese medicines effective in IgA Nephropathy Treatment?

According to the progression of pathological changes, IgA Nephropathy is divided into 5 stages:

Stage 1: there is slight mesangial broadening. No other symptoms occur. Intermittent blood in urine usually is not found.

Stage 2: In mesangial area, there is focal proliferation and sclerosis but no other abnormalities. At this time, there is slightly higher frequency of intermittent blood in urine but it is still hard to be seen.

Stage 3: The proliferation and broaden of mesenchymal area begin to diffuse. Besides, glomerular

Shows crescent. Renal tubular and mesenchyme have focal edema. In this stage, blood urine occurs persistently. Some patients begin to have urine protein and high blood pressure as well as other symptoms.

Stage 4: Mesangial proliferation and sclerosis are severely diffused. Glomerular sclerosis occurs and renal tubular atrophy and renal interstitial infiltration are also aggravated. Glomerular crescent is near to 50% and kidney damage is very severe.

In stage 4, kidney dysfunction occurs. Aside from hematuria, urine protein, high blood pressure and other symptoms are serious. Besides, kidney damage has brought some complications like anemia, electrolyte disorder, bone disease and heart failure, etc.

Stage 5: Glomerular crescent is over 50% and your disease is approaching to end stage. Kidney function declines and some patients have been in uremia stage.

What is the treatment for IgA Nephropathy?

The key point in IgA Nephropathy is to remove IgA immune complexes from mesangial area and stop glomerular sclerosis.

The common treatment for IgA Nephropathy is for symptoms like blood in urine, protein in urine and high blood pressure,etc. The curative effect is not good. Patients can experience frequent relapse. However, our hospital creates Chinese medicine treatments which can improve microcirculation in kidneys and relieve renal ischemia-anoxia state. Besides, Chinese medicines can stop renal cell sclerosis and restore injured but not dead kidney cells. In this way, IgA Nephropathy can be treated effectively.

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Tag: IgA Nephropathy Treatment

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