Will Steroids Cause High Blood Sugar for IgA Nephropathy Patients
IgA Nephropathy is resulted from inflammatory reactions within kidneys. To manage patients' proteinuria and inhibit inflammatory reactions, steroids are often used. However, patients who take steroids are more likely to be at higher risk of high blood sugar or even diabetes.
IgA Nephropathy
Normally, when harmful substances attack the body, the immune system will produce antibodies that can combine antigens to form immune complexes. Then, circulatory system will remove immune complexes from the body. However, when immune system becomes abnormal, the body produces more or fewer antibodies, so the circulatory system can't eliminate immune complexes normally. When excessive amount of IgA is produced and builds up in glomerular mesangial area and they can induce inflammatory reactions, IgA Nephropathy will occur.
How does steroids treat IgA Nephropathy?
Steroids have the anti-inflammatory property that can inhibit the proliferation of connective tissues and reduce the permeability of capillary wall and cell membrane. Additionally, this medicine can reduce the exudation of inflammatory substances.
Steroids and high blood sugar
This medicine can prompt the protein decomposition and make protein break down to sugar, reducing the use of glucose. Thereby, blood sugar and hepatic glycogen both increase, causing sugar in the urine. At the same time, it can increase the secretion of gastric juice and prompt poor appetite. Then, IgA Nephropathy patients who take steroids may get high blood sugar or diabetes.
Is there an alternative therapy to steroids with IgA Nephropathy?
Until now, Immunotherapy has been used widely to replace steroids for treating IgA Nephropathy. Because it can remove the deposits of IgA, regulate the immune system and rebuild kidney filtering system, it can treat IgA Nephropathy fundamentally.
If you want to get rid of steroids and treat your IgA Nephropathy from the root, you can leave a message below or email to kidneyservice@hotmail.com.
Tag: IgA Nephropathy Treatment IgA Nephropathy
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